Moxifloxacin-induced mental status change

can antibiotic induce mental status change?

Moxifloxacin-induced torsade de pointes

Torsade de pointes (TdP) is increasingly recognized as a complication of drug therapy. The most common cause of drug-induced QT prolongation is inhibition of the rapidly activating component of the delayed potassium current (IKr). Moxifloxacin, a widely used fluoroquinolone, is a weak IKr inhibitor and has been associated with QT prolongation. We report a case of marked QT prolongation (618 ms)...

Rapid Change in Mental Status in a Patient with Hypereosinophilia

We present the case of a 48-year-old female with acute onset altered mental status, who was found to have eosinophilia, elevated troponin, and embolic strokes. Extensive testing for autoimmune, infectious, and coronary artery etiologies was unremarkable. After a cardiac MRI revealed focal myocardial hyperenhancement, the patient underwent an endomyocardial biopsy with findings consistent with e...

moxifloxacin induced seizures -a case report.

a 73-year-old female patient developed a generalized tonic-clonic seizure on the 6th day after treatment with moxifloxacin 400 mg daily intravenously for appendicitis. this patient had atrial fibrillation and history of a surgery for intracerebral hemorrhage, with impaired renal function and liver function, but without history of seizures. moxifloxacin was discontinued and switched to cefuroxim...

Moxifloxacin (Avelox) Induced Thrombotic Thrombocytopenic Purpura

We report a case of a 66-year-old African-American female who presented with complaints of progressively worsening weakness, shortness of breath on minimal exertion, lethargy for the last few days, and short episodes of aphasia lasting 20-30 seconds. Prior to presentation, she was treated with two courses of moxifloxacin for sinusitis. Laboratory examination was remarkable for anemia and thromb...